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Adding Probiotic to Lignans Enhances Bioavailability

If you are giving Flaxseed Lignans to your dog with Cushings disease, you may also want to consider giving your dog a probiotic at the same time. Flaxseed lignans involve a two-step digestive process and the SDG lignans found in flaxseed must be broken down in the digestive system before they can be absorbed. The probiotic will help with this breakdown and can increase the absorption rate of the flaxseed lignans.

flax blog pic CID website

Yogurt is a great probiotic if it has live active cultures. Activia is one brand of yogurt with live active cultures and dogs love the taste. In addition to increasing the benefits of the flaxseed lignans, the yogurt can make it easier to give the lignans to your dog. You may open a flaxseed lignan capsule and mix the lignan in with the yogurt. Large amounts of yogurt are not necessary; one tablespoon is usually sufficient to mix with the flaxseed lignans. Note: HMR lignans do not require a probiotic; HMR lignans can be absorbed into the body in a one-step digestive process. Lignans can take up to 4 months before improving symptoms in dogs with Cushings disease, but on average, most dogs (about 85%) respond in two months and have at least one symptom improve during that time.

6 Responses so far.

  1. aiperon91 says:

    my cushings dog is going to receive trilostane. will this interact safely with the melatonin and lignans? thanks

    • Cushings in Dogs says:

      Some vets recommend lignans and melatonin in conjunction with conventional medications; however, we can not speak to your dog’s case in particular as each Cushings case is different. It is very important to consult your veterinarian when introducing new supplements since they are familiar with your dog’s regimen.

  2. christina owens says:

    do you need both the lignans & the melatonin?

    • Cushings in Dogs says:

      Giving both lignans and melatonin is not necessary; however, they are more effective when used together and are often recommended in conjunction with one another. They each inhibit separate enzymes needed in the production of Cortisol, a stress hormone that is produced in excess in dogs with Cushings. Reducing this heightened cortisol can help manage Cushings symptoms. It is important to consult your veterinarian on which they recommend as each Cushing’s case is different and they are more familiar with your dog’s.

  3. Yolanda Bird says:

    My bichon frise has been diagnosed with cushings disease, I have been using Vetoryl capsules 10mg for the last 9 months or so and would like to try a more holistic approach. How would I know what Lignans to use.

    • Cushings in Dogs says:

      If you are considering lignans, either Flaxseed Lignans or HMR Lignans are recommended. The main difference between the two is the fiber content and sourcing; however, studies and research have reported that they both work equally well when it comes to reducing heightened Cortisol levels in Cushingoid dogs. HMR Lignans come from the Norwegian Spruce Tree and do not contain fiber. Flaxseed SDG Lignans come from Flaxseed Hulls and contain fiber. The important factor to consider is the correct dosage for your dog. It is recommended to give your dog 1-2 mg of lignan per pound of body weight (i.e. a 20 lb dog would have 20-40 mg of lignan per day). A site for lignans that we often suggest is lignans.net as they provide quality products and ample information. However, we always recommend consulting your veterinarian when changing your dog’s regimen as they are most familiar with your dog’s particular case. Good luck!

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